Introduction
If your device turns on but the screen is black or if you when take a picture it comes out distorted or blurry, you may need to change the main board. A bad main board can also cause distorted sound or no sound at all.
Tools
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            Open the screen exposing the hinge cover and place the plastic opening tool inside. 
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            Pry the hinge cover up by moving the plastic opening tool in a downward motion. 
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            Remove the black 4mm Phillips #000 screw that is revealed once the hinge cover is removed. 
 
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            Unscrew the two 4 mm Phillips #000 screws on the right hand side of the camera using the screwdriver. 
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            Unscrew five more 4 mm Phillips #000 screws that are located at the bottom of the camera with the screwdriver. 
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            Remove the last exterior 4 mm Phillips #000 screws on the left hand side of the camera with the scredriver. 
 
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            Use the plastic opening tool in a downward motion around each side of the camera to pry the casing open. 
 
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            Locate the black ribbon at the bottom left of the camera's interior. 
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            Place the plastic opening tool under the black ribbon connector. 
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            Remove the cable by moving your plastic opening tool in a downward motion. 
 
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            Lift the black latch of the left main ribbon connector using a wide-set plastic opening tool in a downward motion. 
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            Use your fingers to disconnect the cable. 
 
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            Use the wide-set plastic opening tool to lift the latch on the right main ZIF cable in a downward motion. 
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            Disconnect the cable using your finger. 
 
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            Locate the skinny ZIF cable on the left side of the main board. 
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            Disconnect the cable with the tweezers by pulling it away from where the cable is connected. 
 
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            Locate the black cable connected at the top right of the main board. 
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            Place the wide-set plastic opening tool underneath the gray connector and carefully pry it up. 
 
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To reassemble your device, follow these instructions in reverse order.
4 comments
How do you actually get the mainboard for replacement? Is it directly through Samsung?
Nevermind, the parts are available at Samsungparts.com.
I believe the particular part of interest is the AD92-02282A, although I'll write a followup if this is not correct.
I can now confirm the part is the AD92-02282A. Following this guide worked very well and saved me risking $800 on ebay for a used nx500.
i’ve been told that after replacing the mainboard the camera needs to be adjusted which could only be done by a professional workshop.
did you run into any problems with the new mainboard?